Clinical Virology In the Department of Pathology

Molecular Virology

 Quantitative BK Virus testing by real-time PCR

Molecular Virology refers to the diagnosis of viral disease via the detection and characterization of viral nucleic acids.  The Stanford Clinical Virology Laboratory offers comprehensive molecular virology testing for both the immunocompetent and immunocompromised host. Our molecular virology assays are automated to improve accuracy and reproducibility while minimizing turnaround time. In addition, most assays incorporate real-time PCR technology that links amplification with detection to provide a streamlined, rapid process with minimal risk of contamination and false positive results. See also the Genotyping and Antiviral Resistance testing page for a discussion of our viral sequencing program.

Our Molecular Virology Test Menu Includes:

Qualitative Assays:

  • Influenza A RNA detection in Nasopharyngeal (NP) Swab specimens or Bronchoalveolar Lavage
    (BAL) fluid for the diagnosis of influenza A infection
  • Influenza A 2009 (H1N1) subtyping and oseltamivir (Tamiflu) resistance testing to determine optimal
    antiviral therapy
  • Herpes Simplex Virus (HSV) DNA detection in Cerebrospinal Fluid (CSF)
    for the diagnosis of Herpes Encephalitis
  • N. gonorrhoeae and C. trachomatis DNA detection for the diagnosis of Chlamydial and Gonococcal
    genital tract infections
  • Human Papilloma Virus (HPV) DNA detection of high risk types for cervical cancer screening triage

Quantitative Viral Load Assays:

For Monitoring Chronic Viral Disease:

  • Human Immunodeficiency Virus-1 (HIV-1) RNA
  • Hepatitis B Virus (HBV) DNA
  • Hepatitis C Virus (HCV) RNA

For Monitoring Viral Reactivation in immunocompromised/transplant patients:

  • Cytomegalovirus (CMV) DNA
  • Epstein-Barr Virus (EBV) DNA
  • BK virus DNA

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